Diagnosis of cirrhosis based on regional changes in hepatic morphology: a radiological and pathological analysis.
Harbin WP, Robert NJ, Ferrucci JT Jr. Radiology 1980 May;135(2):273-83 Related Articles, Links
Transverse images of cirrhotic
livers revealed specific morphological changes. The right lobe
exhibited relatively greater shrinkage, while the caudate lobe
underwent relative enlargement. Sonograms or CT scans of 25 proved
cirrhotic livers, 25 normal livers, and 15 livers with diffuse
disease other than cirrhosis were analyzed using a number of measurements
and ratios to evaluate and quantify the frequency and possible
diagnostic value of these alterations. Using the ratio of transverse
caudate lobe width to transverse right lobe width, cirrhotic livers
could be separated from noncirrhotic liver (both normal and abnormal)
with a sensitivity of 84%, a specificity of 100%, and an accuracy
of 94%. Another ratio revealed relative widening of the porta
hepatis in 84% of cirrhotic livers, but this was not specific
for cirrhosis. Pathological analysis of 11 cirrhotic cadaver livers
revealed greater fibrosis in the right lobe than in the caudate
lobe.
| Retour au texte | Sommaire |