Assessing liver function by magnetic resonance imaging two-dimensional phase-shift flow measurement of portal venous blood flow after oral intake of glucose
Yagi H, Midorikawa T, Sakamoto M, Masuda E, Saitoh M, Takeyama Y, Haku E, Ishibashi K, Nemoto H, Kikuchi H, Sasaya S, Yamaguchi M, Sanada Y, Kumada K.Nippon Geka Gakkai Zasshi 2002 May;103(5):441-7
We have already reported
that the ratio of portal venous flow 30 min after oral intake
of glucose 75 g to that before intake (PVFR30), measured using
pulsed-Doppler ultrasonography (US), correlated significantly
with other indicators of liver function and that it could be used
to estimate hepatic function before surgery, including liver resection.
In this study, to assess the disadvantages of pulsed-Doppler ultrasonography,
PVFR30 was measured using two-dimensional (2D) phase-shift (PS)
magnetic resonance imaging (MRI). PVFR30 was measured in 17 patients
and 7 volunteers: 13 with liver cirrhosis (LC) and 11 without
LC (non-LC). Portal venous flow could be measured in all patients
without any disturbance of intestinal gas or patient fat, or the
high degree of technical skill that Doppler US requires. PVFR30
was significantly lower in the LC group than in the non-LC group.
In addition, it correlated significantly with other indicators
of liver function, including the indocyanine green clearance test,
prothrombin time, hepaplastin test, and cholinesterase activity.
These results suggest that PVFR30 measured by 2D PS MRI can be
used to estimate liver function, and that this MRI method can
be performed more easily than pulsed-Doppler US.
| Retour au texte | Sommaire |