OBJECTIVE: The purpose of this study was to describe central dot sign (tiny dots with strong
                       contrast enhancement of the portal vein within dilated hepatic bile ducts on computed
                       tomography) in entities other than Caroli disease, especially in peribiliary cysts with or without
                       autosomal-dominant polycystic kidney disease. MATERIALS AND METHODS: Computed
                       tomography in 74 cases of peribiliary cysts and 134 cases of other liver diseases and states
                       possibly showing central dot sign were retrospectively reviewed to examine the central dot sign.
                       RESULTS: In three cases of peribiliary cysts, some part of the liver showed strongly enhanced
                       portal radicles surrounded completely or partially by low-attenuation, enlarged peribiliary cysts,
                       presenting "central dot sign" on contrast-enhanced computed tomography. CONCLUSION: We
                       suggest that in addition to Caroli disease, some other entities and diseases of the liver may
                       demonstrate central dot sign and this sign should not be considered a specific finding of Caroli
                       disease.Asselah T; Ernst O; Sergent G; L'hermine C; Paris JC Caroli's disease: a magnetic resonance cholangiopancreatography diagnosis. Am J Gastroenterol  1998 Jan;93(1):109-10

 

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