MultiHance in the dynamic phase of contrast enhancement: a pictorial assessment.
Grazioli L, Kirchin M, Pirovano G, Spinazzi A.J Comput Assist Tomogr 1999 Nov;23 Suppl 1:S61-4
The present article demonstrates
pictorially the use of MultiHance (gadobenate dimeglumine, Gd-BOPTA)
in dynamic magnetic resonance imaging and is aimed at ensuring
that the product is not misconceived as solely a hepatobiliary
agent for use in delayed, static magnetic resonance imaging for
the improved detection of focal liver lesions. The enhancement
patterns of three malignant (hepatocellular carcinoma, cholangiocarcinoma
and metastasis) and three benign (hemangioma, focal nodular hyperplasia
and adenoma) lesion types are demonstrated. Each was imaged during
the dynamic phase of contrast enhancement immediately following
the intravenous bolus administration of 0.05 mmol/kg MultiHance.
The article demonstrates that the enhancement patterns observed
for these relatively common lesions are similar to those reported
in the literature after the intravenous bolus administration of
conventional, non-specific 'extracellular fluid' contrast agents,
and concludes by inferring that MultiHance behaves in the liver
as a conventional gadolinium-based agent in the first minutes
after administration.
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